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Lumps, Bumps, and Beyond: A Guide to your Skin and Soft Tissue Mass

Apr 19

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Skin and soft tissue masses are lumps or growths that form under the skin or within the soft tissues of the body, such as muscles, fat, nerves, and connective tissue. This is a very broad subject and encompasses a wide range of diseases. While most of these masses are benign (non-cancerous), some may require medical attention due to their potential to grow, cause discomfort, or, in rare cases, become malignant.

In this blog post, we’ll explore the common types, causes, symptoms, and treatment options for skin and soft tissue masses, as well as when to seek medical advice.


What Are Skin and Soft Tissue Masses?


A skin or soft tissue mass refers to an abnormal growth of cells that forms a lump or bump under the skin. These masses can vary greatly in size, texture, and location. Some are superficial and visible on the skin, while others develop deeper in the tissues and may only be detected through imaging studies. Superficial lesions are amenable for in office procedures while deeper lesions may require outpatient surgery. Sometimes, it can be hard to distinguish between these lesions and if uncertainty remains it may require removal to confirm diagnosis


Common Types of Skin and Soft Tissue Masses


  1. Benign Masses:

    • Lipomas: Soft, fatty lumps that grow slowly and are usually painless.


      Large Lipoma on shoulder
      Large Lipoma with discrete edges. This will require an incision as large as the diameter of the lesion for effective removal

    • Sebaceous cysts: Fluid-filled sacs caused by blocked sebaceous glands.


      Superficial skin lesion likely a sebaceous cyst
      Sebaceous or inclusion cyst under the skin. These can sometimes become infected leading to a skin abscess
    • Fibromas: Firm, fibrous lumps made of connective tissue.

    • Hemangiomas: Non-cancerous growths of blood vessels, often appearing as red or purplish spots.


      skin lesion showing a hemangioma
      Typical benign Hemangioma
    • Neurofibromas: Benign nerve sheath tumors that may occur in individuals with neurofibromatosis.

  2. Infectious or Inflammatory Masses:

    • Abscesses: Painful collections of pus caused by bacterial infections.


      Superficial skin Abscess
      Skin Abscess with associated fluctuance and redness that will require Incision and Drainage for effective treatment with antibiotics

    • Granulomas: Localized areas of inflammation due to infection or foreign material.

  3. Malignant (Cancerous) Masses:

    • Soft tissue sarcomas: Rare cancers that arise in soft tissues like fat, muscle, or connective tissue.


      Large fungating skin lesion
      Large and rapidly enlarging mass involving the skin and subcutaneous tissues requiring wide radical excision

    • Skin Cancer and Melanomas: Aggressive skin cancers that can form masses, especially if advanced. Requires detailed physical examination


      Skin lesion likely a melanoma undergoing physical examination
      Detailed examination of a superficial skin lesion with irregular edges with high suspicion for melanoma including Asymmetry, Borders irregularity, Color variation, Diameter and evolution over time.

Causes of Skin and Soft Tissue Masses


The underlying causes vary depending on the type of mass and may include:

  • Genetic predisposition (e.g., lipomas or neurofibromas).

  • Blocked glands or ducts (e.g., sebaceous cysts).

  • Trauma or injury leading to inflammation.

  • Infections causing abscess formation.

  • Abnormal cell growth or mutations (e.g., sarcomas or melanomas).



Symptoms to Watch For


The symptoms of skin and soft tissue masses depend on their location, size, and type. Common symptoms include:

  • Visible lump: A noticeable bump or swelling under the skin.

  • Pain or tenderness: Especially in abscesses or growing masses.

  • Changes in size: Rapid growth may be a sign of malignancy.

  • Skin changes: Redness, discoloration, or warmth over the lump.

  • Restricted movement: If the mass presses against muscles or joints.


When to See a Doctor


While many masses are harmless, it’s important to consult a healthcare provider if you notice:

  • A rapidly growing or large mass.

  • Persistent pain or discomfort.

  • Changes in color, texture, or appearance.

  • A mass that feels hard, fixed, or immovable.

  • Signs of infection, such as redness, warmth, or pus drainage.


Diagnosing Skin and Soft Tissue Masses


Doctors use various methods to evaluate a mass, including:

  • Physical examination: Assessing the size, shape, and texture.

  • Imaging studies: Ultrasound, MRI, or CT scans can help determine the depth and composition of the mass.

  • Biopsy: Taking a tissue sample for laboratory analysis to rule out malignancy is the best diagnostic modality if malignancy suspected. This can be performed in a simple office procedure.


Treatment Options


Benign Masses: Most benign masses do not require treatment unless they cause discomfort, functional issues, or cosmetic concerns. When necessary, options include surgical excision or drainage. It’s important to note that drainage—commonly used for cysts—is typically a temporary solution. To prevent recurrence, complete removal of the cyst and its capsule is recommended.


Infectious Masses: These are typically treated with a combination of antibiotics and surgical intervention. Antibiotics alone are often insufficient without proper drainage of the infection. Incision and drainage (I&D) is a common, effective procedure that can usually be performed in an office setting, urgent care, or the emergency department.


Malignant Masses: Treatment of cancerous masses involves a multidisciplinary approach. When detected early, surgical removal may be curative. However, depending on the type and stage of the cancer, additional therapies such as chemotherapy and radiation may be required to ensure comprehensive treatment.


Preventing Skin and Soft Tissue Masses


While not all masses can be prevented, certain measures can reduce your risk:

  • Maintain good skin hygiene to prevent infections.

  • Protect your skin from trauma and UV exposure.

  • Seek prompt medical attention for unusual growths or wounds.

  • Monitor existing lumps for any changes.


Skin and soft tissue masses encompass a wide spectrum of conditions—from benign growths like lipomas and cysts to more serious infections and malignant tumors. While many of these masses are harmless and may not require treatment, others can lead to complications if left untreated. Recognizing the signs—such as rapid growth, pain, or changes in appearance—and seeking timely medical evaluation is essential for accurate diagnosis and effective management.


Thanks to advancements in diagnostic tools and minimally invasive procedures, many masses can be evaluated and treated efficiently in outpatient settings. Whether a simple in-office removal or a multidisciplinary approach for complex or malignant cases is needed, early intervention is key to achieving the best possible outcome.


If you’ve noticed a new lump or are concerned about an existing one, don’t ignore it. At Intercoastal Medical Group, we offer expert evaluation and personalized care for patients throughout Sarasota, Lakewood Ranch, and Bradenton. Let our team help you find clarity, peace of mind, and the right treatment plan tailored to your needs.

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